Endocrine Abstracts

According to the novel concept bone remodeling is centrally regulated (CNS). Leptin the adipocyte derived hormone acts on hypothalamus and by increasing sympathetic activity acts on osteoblasts to regulate bone formation. In patients with schizophrenia several factors have influence on bone metabolism. Schizophrenia per se, as a disease of central nervous system is associated with increased occurence of osteoporosis. Hyperprolactinemia as consequence of antipsychotic tr...

Schizophrenia is a devastating mental illness associated with obesity and diabetes mellitus rates that far exceed those of the general population.The aim was to evaluate changes in positive energy balance (serum insulin, leptin and ghrelin) and hormones involved in neuroendocrine regulations (serum cortisol, growth hormone and prolactin) before treatment with atypical antypsyhotics (SGA) in normal weight patients with schizophrenia.<p class="abstext"...